Arginine is a non-essential amino acid that’s naturally synthesized in the body. It’s found mostly in connective tissue and skin and is responsible for tissue repair and rapid healing.1 It plays an important role in wound healing and hormone secretions.2 One type known as L-arginine has been shown to have many health benefits when added to the diet or taken as supplements. As an amino acid, L-arginine helps build proteins within the body. It can be found in animal products like fish, poultry, red meat, and dairy products, as well as in supplement form.3
L-Arginine Uses and Health Benefits
L-arginine supplements have long been used to improve athletic performance, prevent the common cold, and boost the immune system.3 The amino acid also helps with a range of circulatory system problems. For example, it helps dilate the blood vessels to decrease blood pressure and may help women with preeclampsia, a condition characterized by high blood pressure during pregnancy.4, 5
Since L-arginine benefits include its ability to improve blood circulation, it’s said to help patients with syncope, which refers to fainting due to decreased blood flow to the brain.6 It can even help relieve leg pain due to blocked arteries, a condition known as intermittent claudication, or poor blood flow, which is known as peripheral artery disease. Further L-arginine benefits
L-Arginine Side Effects and Precautions
Although L-arginine uses are vast, it’s important to take L-arginine supplements with caution. Since L-arginine increases blood flow and lowers blood pressure, it may interact with medications for high blood pressure and erectile dysfunction.4 It may also interact with diabetes or blood thinning medications.7 Talk to your doctor before taking L-arginine if you have a history of low blood pressure, heart attack, or heart disease.6 Avoid if you have kidney or liver disease.7
Among L-arginine side effects, it may worsen herpes, including cold sores, by stimulating replication of the virus. Consult your doctor before taking L-arginine supplements when pregnant to ensure you receive the proper dose. Do not give L-arginine supplements to young children or infants as it can interact with their natural growth.1
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